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Local Knowledge and Experiences of Vaccination: Implications for HIV-Preventive Vaccine Trials in South Africa

School of Psychology, and HIV/AIDS Vaccine Ethics Group, University of KwaZulu-Natal, Scottsville, South Africa, Lindegger{at}ukzn.ac.za

Michael Quayle, MA

School of Psychology, University of KwaZulu-Natal, Scottsville, South Africa

Moses Ndlovu, BCom (HOns)

HIV/AIDS Vaccine Ethics Group, University of KwaZulu-Natal, Scottsville, South Africa

This study forms part of the preparation of communities for HIV-preventive vaccine trials in South Africa. On the basis of the assumption that attitudes to any HIV vaccine or vaccine trials will partly be influenced by experiences of vaccination in general, this study aimed to investigate knowledge of, attitudes to, and experiences of vaccination in a small semirural community in KwaZulu-Natal, South Africa. The study also sought to investigate the effect of traditional, cultural, and religious beliefs on attitudes to vaccination, as well as to get some indication of willingness to participate in potential HIV vaccine trials. Overall, the findings reveal a good knowledge of, and positive attitudes to, vaccination, with little negative effect of traditional, cultural, and religious beliefs. The findings also reveal a generally positive attitude to HIV vaccines and vaccine trials. Barriers identified, such as anxiety about safety, were not surprising.

Key Words: HIV/AIDS • vaccination • clinical trials • knowledge

This version was published on February 1, 2007

Health Education & Behavior, Vol. 34, No. 1, 108-123 (2007)
DOI: 10.1177/1090198105277852


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